Introduction
Resveratrol रेस्वेराट्रोल, a naturally occurring compound found in grapes and red wine, is used for its various potential health benefits, including antioxidant, anti-inflammatory, and cardioprotective effects. It is also explored for its potential in treating conditions like cancer, diabetes, and neurodegenerative diseases. While research is ongoing, resveratrol is a topic of interest in the fields of preventative medicine, aging, and overall health.
chemical nature:
Resveratrol is a stilbene polyphenol with the chemical formula C14H12O3, possessing two aromatic rings linked by an ethylene bridge. It exists in two isomeric forms, cis and trans, with the trans form being more stable and prevalent in food sources. The molecule has hydroxyl (-OH) groups at specific positions on the aromatic rings, contributing to its chemical properties and biological activity.
Natural souces of resveratrol :
Foods high in resveratrol::
It is produced by plant sources such as red grapes, apples, blueberries, plums, and peanut.
Foods highest in resveratrol include red wine, red grapes, peanuts, blueberries, cranberries, and mulberries. Red wine, due to its fermentation process using red grape skins, is a particularly good source..
Blueberries, cranberries, and mulberries are also good sources of resveratrol. .
In general, the resveratrol content of red wine is higher than that of white wine.
Among the samples analyzed, mulberry fruit (whole) showed highest resveratrol content (50.61 μg g−1 dry weight) followed by jamun seed.
Dark chocolate, black tea, and cocoa powder also contain resveratrol, albeit in smaller amounts.
Japanese Knotweed:
While not typically consumed in the same way as food, Japanese knotweed (Polygonum japonicum) is a known source of resveratrol and is used in traditional Chinese medicine, according to a study published by the National Institutes of Health (NIH).
•Potential Health benefits of Resveratrol:
Resveratrol, a naturally occurring compound found in red grapes, berries, and other plants, is associated with a variety of potential health benefits, including antioxidant, anti-inflammatory, and cardioprotective effects. It may also help protect against certain cancers, promotes brain health, and contributes to overall well-being.
(1) Antioxidant and Anti-inflammatory Properties:
Resveratrol's antioxidant properties help protect cells from damage caused by free radicals, while its anti-inflammatory effects may reduce swelling and irritation.
(2) Cardioprotective Effects:
Resveratrol may help protect the heart by reducing blood clotting, lowering LDL cholesterol, and preventing damage to blood vessels.
(3) Blood sugar regulation Resveratrol has demonstrated health benefits for people with Type 2 diabetes in several studies. For example, researchers commonly see improvements in serum lipid (cholesterol) and glucose levels after treating test subjects with resveratrol.
Resveratrol may help improve insulin sensitivity and regulate blood sugar levels, potentially benefiting individuals with diabetes.
(4) Anti-aging effects. Resveratrol has been shown to cause the prevention of aging and many other health benefits. Numerous reports confirmed that resveratrol exhibits anti-aging and regenerative effects on the skin. The primary purpose of the action of natural products may be to regulate the expression of miRNA, which leads to cell death or prevents aging, diabetes, cardiovascular diseases, and other diseases.
(5) Protects brain
Resveratrol is a naturally occurring polyphenol with the chemical name 3,5,4'-trihydroxystilbene. It exhibits neuroprotective properties in the brain, including antioxidant and anti-inflammatory effects. These effects can help protect against various brain-related conditions, such as neurodegenerative diseases and stroke.
Neuroprotective Effects:
Studies suggest that resveratrol can protect brain cells and improve cognitive function, potentially slowing down the progression of age-related cognitive decline.
(6) In kidney diseases, resveratrol could safely improve peritoneal ultrafiltration activity and ameliorate renal dysfunction .
(7) Liver protection Resveratrol can provide Liver protection against chemical, cholestatic, and alcohol-mediated damage. It can improve glucose metabolism and lipid profile, reduce liver fibrosis, and steatosis. Additionally, it is capable of altering the fatty acid composition of the liver cells.
(8) Anti-cancer property
Resveratrol may have anticancer properties, potentially reducing the risk of certain types of cancer and interfering with the growth and spread of cancerous cells.
As a natural food ingredient, numerous studies have demonstrated that resveratrol possesses a very high antioxidant potential. Resveratrol also exhibit antitumor activity, and is considered a potential candidate for prevention and treatment of several types of cancer.
(9) Skin brightening:
Enhancing Skin Protection: Resveratrol can inhibit the production of melanin and as such help fade age spots and even out skin tone. : By fortifying the skin's barrier function, it helps protect the skin from external harm and excess water loss.
(10) Molecule of eternal youth:
It's said to have anti-oxidative, anti-inflammatory, and—yes—anti-aging effects. Best of all, this natural “molecule of eternal youth” is found in some of my favorite foods, including red wine, chocolate, and raspberries.
(11) Good for hair growth:
Resveratrol has anti-inflammatory and antioxidant properties. By protecting hair follicles from damage and inflammation, resveratrol may help prevent shedding and support the normal hair growth cycle. This might explain why some research indicates that resveratrol can protect sun-damaged hair.
investigated.
•How Resveratrol Works:
Antioxidant: Resveratrol neutralizes free radicals, unstable molecules that can damage cells and contribute to chronic diseases.
Anti-inflammatory:
Resveratrol reduces inflammation by inhibiting the production of inflammatory molecules.
Cardioprotective:
Resveratrol may promote healthy blood vessels, reduce blood clotting, and lower cholesterol levels.
Neuroprotective:
Resveratrol protects brain cells from damage and may improve cognitive function.
Important Considerations:
While resveratrol is generally considered safe, it's essential to consult with a healthcare professional before taking it as a supplement, especially if you have any underlying health conditions or are taking medications.
The benefits of resveratrol are primarily observed in animal and cell-based studies, and more research is still needed to confirm these effects in humans.
The optimal dosage and duration of resveratrol supplementation are still being investigated
Normal dose of supplement: Resveratrol has most often been used by adults in doses of 250-1000 mg by mouth daily for up to 3 months. It is also sometimes used in nasal sprays.
Where to buy resveratrol suppliment ?
Nutrabay.com is India's most trusted leading online website for the best resveratrol supplement for men and women. Products sold on Nutrabay are 100% authentic as they are sourced either directly from the brands or official importers.
Resveratrol supplements are commonly available under various brand names like Nutricost, Reserveage, 1mg, and Amazon.in. Other brand names include Biotrex, Fitness Veda, and Decode Age. Additionally, brands like Sharrets, Kaibro Nutra, and Pure Encapsulations also offer resveratrol supplements.
•The negative side effects of resveratrol:
(1) Resveratrol, a naturally occurring compound, generally has a low toxicity level and is well-tolerated at moderate doses. However, higher doses can lead to side effects, primarily gastrointestinal issues like nausea, diarrhea, and abdominal pain.
Whereas resveratrol appears to be well tolerated in some studies, high doses can cause gastrointestinal side effects such as diarrhoea . It also inhibits CYP450 enzymes and may increase the risk of adverse effects of certain drugs..
Gastrointestinal issues:
Nausea, vomiting, diarrhea, and abdominal pain are the most frequently reported side effects at higher doses.
Interactions with medications:
(2) Avoid taking resveratrol if you have hormone-sensitive conditions such as uterine fibroids, endometriosis, uterine cancer, ovarian cancer or breast cancer.
People who have health conditions like bleeding disorders should not take resveratrol without talking to a doctor first.
(3) There's also a potential for interactions with certain medications, particularly those that affect blood clotting or liver metabolism.
Resveratrol can interact with blood thinners, potentially increasing the risk of bleeding, and may affect how the liver processes other medications.
(4) Other potentia side l effects:
While less common, some studies suggest potential impacts on liver function, particularly in individuals with fatty liver disease, and a possible link to DNA damage.
Important Considerations:
Dose:
The majority of reported side effects are associated with higher doses, often exceeding 2.5 grams per day.
Individual variability:
Individuals may experience different reactions to resveratrol, and those with pre-existing conditions or taking medications should consult with a healthcare professional.
In terms of supplements with resveratrol, they might interact with blood thinners, aspirin and ibuprofen, so talk to your doctor before taking resveratrol supplements.
Limited research:
While studies suggest generally safe use, more research is needed to fully understand the long-term effects and potential risks, especially in specific populations like those with liver or kidney problems.
Despite these results, resveratrol still carries some uncertainties and controversies. One significant uncertainty surrounding resveratrol is its poor bioavailability when taken orally. Studies have shown that resveratrol is rapidly metabolized and excreted, resulting in limited bioavailability
Finally we can say that
Resveratrol in its natural form in foods and as a supplement helps in well being and longevity.
Information complied by Dr. Bhairavsinh Raola naturally occurring compound found in grapes and red wine, is used for its various potential health benefits, including antioxidant, anti-inflammatory, and cardioprotective effects. It is also explored for its potential in treating conditions like cancer, diabetes, and neurodegenerative diseases. While research is ongoing, resveratrol is a topic of interest in the fields of preventative medicine, aging, and overall health.
chemical nature:
Resveratrol is a stilbene polyphenol with the chemical formula C14H12O3, possessing two aromatic rings linked by an ethylene bridge. It exists in two isomeric forms, cis and trans, with the trans form being more stable and prevalent in food sources. The molecule has hydroxyl (-OH) groups at specific positions on the aromatic rings, contributing to its chemical properties and biological activity.
Natural souces of resveratrol :
Foods high in resveratrol::
It is produced by plant sources such as red grapes, apples, blueberries, plums, and peanut.
Foods highest in resveratrol include red wine, red grapes, peanuts, blueberries, cranberries, and mulberries. Red wine, due to its fermentation process using red grape skins, is a particularly good source..
Blueberries, cranberries, and mulberries are also good sources of resveratrol. .
In general, the resveratrol content of red wine is higher than that of white wine.
Among the samples analyzed, mulberry fruit (whole) showed highest resveratrol content (50.61 μg g−1 dry weight) followed by jamun seed.
Dark chocolate, black tea, and cocoa powder also contain resveratrol, albeit in smaller amounts.
Japanese Knotweed:
While not typically consumed in the same way as food, Japanese knotweed (Polygonum japonicum) is a known source of resveratrol and is used in traditional Chinese medicine, according to a study published by the National Institutes of Health (NIH).
•Potential Health benefits of Resveratrol:
Resveratrol, a naturally occurring compound found in red grapes, berries, and other plants, is associated with a variety of potential health benefits, including antioxidant, anti-inflammatory, and cardioprotective effects. It may also help protect against certain cancers, promotes brain health, and contributes to overall well-being.
(1) Antioxidant and Anti-inflammatory Properties:
Resveratrol's antioxidant properties help protect cells from damage caused by free radicals, while its anti-inflammatory effects may reduce swelling and irritation.
(2) Cardioprotective Effects:
Resveratrol may help protect the heart by reducing blood clotting, lowering LDL cholesterol, and preventing damage to blood vessels.
(3) Blood sugar regulation Resveratrol has demonstrated health benefits for people with Type 2 diabetes in several studies. For example, researchers commonly see improvements in serum lipid (cholesterol) and glucose levels after treating test subjects with resveratrol.
Resveratrol may help improve insulin sensitivity and regulate blood sugar levels, potentially benefiting individuals with diabetes.
(4) Anti-aging effects. Resveratrol has been shown to cause the prevention of aging and many other health benefits. Numerous reports confirmed that resveratrol exhibits anti-aging and regenerative effects on the skin. The primary purpose of the action of natural products may be to regulate the expression of miRNA, which leads to cell death or prevents aging, diabetes, cardiovascular diseases, and other diseases.
(5) Protects brain
Resveratrol is a naturally occurring polyphenol with the chemical name 3,5,4'-trihydroxystilbene. It exhibits neuroprotective properties in the brain, including antioxidant and anti-inflammatory effects. These effects can help protect against various brain-related conditions, such as neurodegenerative diseases and stroke.
Neuroprotective Effects:
Studies suggest that resveratrol can protect brain cells and improve cognitive function, potentially slowing down the progression of age-related cognitive decline.
(6) In kidney diseases, resveratrol could safely improve peritoneal ultrafiltration activity and ameliorate renal dysfunction .
(7) Liver protection Resveratrol can provide Liver protection against chemical, cholestatic, and alcohol-mediated damage. It can improve glucose metabolism and lipid profile, reduce liver fibrosis, and steatosis. Additionally, it is capable of altering the fatty acid composition of the liver cells.
(8) Anti-cancer property
Resveratrol may have anticancer properties, potentially reducing the risk of certain types of cancer and interfering with the growth and spread of cancerous cells.
As a natural food ingredient, numerous studies have demonstrated that resveratrol possesses a very high antioxidant potential. Resveratrol also exhibit antitumor activity, and is considered a potential candidate for prevention and treatment of several types of cancer.
(9) Skin brightening:
Enhancing Skin Protection: Resveratrol can inhibit the production of melanin and as such help fade age spots and even out skin tone. : By fortifying the skin's barrier function, it helps protect the skin from external harm and excess water loss.
(10) Molecule of eternal youth:
It's said to have anti-oxidative, anti-inflammatory, and—yes—anti-aging effects. Best of all, this natural “molecule of eternal youth” is found in some of my favorite foods, including red wine, chocolate, and raspberries.
(11) Good for hair growth:
Resveratrol has anti-inflammatory and antioxidant properties. By protecting hair follicles from damage and inflammation, resveratrol may help prevent shedding and support the normal hair growth cycle. This might explain why some research indicates that resveratrol can protect sun-damaged hair.
investigated.
•How Resveratrol Works:
Antioxidant: Resveratrol neutralizes free radicals, unstable molecules that can damage cells and contribute to chronic diseases.
Anti-inflammatory:
Resveratrol reduces inflammation by inhibiting the production of inflammatory molecules.
Cardioprotective:
Resveratrol may promote healthy blood vessels, reduce blood clotting, and lower cholesterol levels.
Neuroprotective:
Resveratrol protects brain cells from damage and may improve cognitive function.
Important Considerations:
While resveratrol is generally considered safe, it's essential to consult with a healthcare professional before taking it as a supplement, especially if you have any underlying health conditions or are taking medications.
The benefits of resveratrol are primarily observed in animal and cell-based studies, and more research is still needed to confirm these effects in humans.
The optimal dosage and duration of resveratrol supplementation are still being investigated
Normal dose of supplement: Resveratrol has most often been used by adults in doses of 250-1000 mg by mouth daily for up to 3 months. It is also sometimes used in nasal sprays.
Where to buy resveratrol suppliment ?
Nutrabay.com is India's most trusted leading online website for the best resveratrol supplement for men and women. Products sold on Nutrabay are 100% authentic as they are sourced either directly from the brands or official importers.
Resveratrol supplements are commonly available under various brand names like Nutricost, Reserveage, 1mg, and Amazon.in. Other brand names include Biotrex, Fitness Veda, and Decode Age. Additionally, brands like Sharrets, Kaibro Nutra, and Pure Encapsulations also offer resveratrol supplements.
•The negative side effects of resveratrol:
(1) Resveratrol, a naturally occurring compound, generally has a low toxicity level and is well-tolerated at moderate doses. However, higher doses can lead to side effects, primarily gastrointestinal issues like nausea, diarrhea, and abdominal pain.
Whereas resveratrol appears to be well tolerated in some studies, high doses can cause gastrointestinal side effects such as diarrhoea . It also inhibits CYP450 enzymes and may increase the risk of adverse effects of certain drugs..
Gastrointestinal issues:
Nausea, vomiting, diarrhea, and abdominal pain are the most frequently reported side effects at higher doses.
Interactions with medications:
(2) Avoid taking resveratrol if you have hormone-sensitive conditions such as uterine fibroids, endometriosis, uterine cancer, ovarian cancer or breast cancer.
People who have health conditions like bleeding disorders should not take resveratrol without talking to a doctor first.
(3) There's also a potential for interactions with certain medications, particularly those that affect blood clotting or liver metabolism.
Resveratrol can interact with blood thinners, potentially increasing the risk of bleeding, and may affect how the liver processes other medications.
(4) Other potentia side l effects:
While less common, some studies suggest potential impacts on liver function, particularly in individuals with fatty liver disease, and a possible link to DNA damage.
e
Important Considerations:
Dose:
The majority of reported side effects are associated with higher doses, often exceeding 2.5 grams per day.
Individual variability:
Individuals may experience different reactions to resveratrol, and those with pre-existing conditions or taking medications should consult with a healthcare professional.
In terms of supplements with resveratrol, they might interact with blood thinners, aspirin and ibuprofen, so talk to your doctor before taking resveratrol supplements.
Limited research:
While studies suggest generally safe use, more research is needed to fully understand the long-term effects and potential risks, especially in specific populations like those with liver or kidney problems.
Despite these results, resveratrol still carries some uncertainties and controversies. One significant uncertainty surrounding resveratrol is its poor bioavailability when taken orally. Studies have shown that resveratrol is rapidly metabolized and excreted, resulting in limited bioavailability
Finally we can say that
Resveratrol in its natural form in foods and as a supplement helps in well being and longevity.
Information complied by Dr. Bhairavsinh Raol
